Merge Plugins Standalone/zMerge: Automated merging can potentially cause major breakage in mods, especially heavily-scripted ones. ZEdit/zClean: Neither have any real advantages over 圎dit, and lack some essential features/support than 圎dit has. They will also often miss critical conflicts. They will solve things that they may see as conflicts but it reality are intentional overwrites. Wrye Bash/Flash and Mator Smash: Similarly to LOOT, these programs are fully automated and will never be fully accurate. Load order on its own will almost never be able to fully solve conflicts, which is why conflict resolution is incredibly important. Incorrect load order can lead to overwriting or breaking features from mods.
LOOT: As LOOT is automated, it will never fully be able to account for all the nuances of a load order, especially a large one. There is no reason to use Mod Organizer 1 over Mod Organizer 2. Mod Organizer 1: Although Mod Organizer 2 is 64bit and was designed for 64 bit games, it works perfectly with Fallout 3/New Vegas. Nexus Mod Manager/Fallout Mod Manager: Outdated/abandoned, have no virtual file system or even dynamic movement of mods with loose files. Vortex: Lacks many essential features, such as manual load order control or a virtual file system.