The longevity of the life of a Quarter Horse is dependent on the care that is provided throughout its lifespan along with other factors like genetics and the size of the horse. So, what is the average lifespan of an American Quarter Horse? The average lifespan of an American Quarter Horse is generally in between 25 to 35 years of age while some can even live longer. Owing to medical advances and improved veterinary care, Quarter Horses can live longer than their usual ages.